Loud S1

Causes of Loud S1  
Condition Mechanism
Short P-R interval (0.08-0.12 second) Valve wide open from recent atrial contraction
Premature beats, tachycardia Valves wide open from rapid early diastolic filling
Mitral stenosis, tricuspid stenosis, atrial myxoma Texture of valve; valve maximally open from prolonged ventricular filling
Exercise, fever, anemia, thyrotoxicosis, epinephrine, anxiety, pregnancy, A-V fistula Forcible ventricular contraction (plus tachycardia)
Thin chest wall, child Minimal damping effects

 

 

Patient 1:

This patient has severe mitral stenosis with a loud S1. The other features of mitral stenosis, including the opening snap and diastolic murmur, are not appreciable in this recording.

Loud S1

Annotated

Patient 2:

This patient was admitted to the hospital after suffering multiple embolic events (to brain and kidney) and an episode of severe hemoptysis, and was later determined to have severe mitral stenosis. One of the classic features of mitral stenosis is a loud S1, demonstrated in these videos. You may also note the opening snap and rumbling diastolic murmur with pre-systolic accentuation.

Loud S1

Annotated

Loud S1

Annotated