Petechiae and purpura are the result of extravasation of blood from the vasculature into the skin or mucosa, usually occurring in the dependent regions of the body. Petechiae are pinpoint hemorrhages ≤2 mm in size, purpura are 2 mm to 1 cm in size, and ecchymoses are >1 cm in size. These lesions do not blanch with pressure.
One of the neutrophilic dermatoses, Sweet’s syndrome can be idiopathic, malignancy-associated, and drug-induced. It presents with tender erythematous skin lesions in the form of papules, nodules, and/or plaques.
Characterized by the sudden development of multiple seborrheic keratoses, associated with an underlying malignancy.
A condition in which abnormal proteins are deposited throughout the tissues of the body. Characteristic physical findings include macroglossia, enlarged shoulders (shoulder pad sign), and purpura (including racoon eyes).
Usually manifests as a palpable and/or visible mass in the breast. A particular subtype, called inflammatory breast cancer, presents with breast swelling and thickening and hardening of the skin overlying the lesion resembling an orange peel (peau d’orange).
Sources and further reading:
- Leung AK, Chan KW. Evaluating the child with purpura. Am Fam Physician. 2001;64(3):419-428.