Pemberton’s Sign

Pemberton’s sign describes the onset of facial plethora after raising the arms above the head, and is found in conditions such as superior vena cava syndrome and large goiter.

 

 

Patient 1:

This is a middle-aged smoker who presented with increasing dyspnea and was found to have a right apical mass complicated by superior vena cava syndrome. The mass was later determined to be small cell lung cancer.

Patient 2:

This is an older man who presented with increasing dyspnea and was found to have a right apical mass complicated by superior vena cava syndrome. The mass was later determined to be non-small cell lung cancer.

This patient also has Horner’s syndrome.