Soft tissue enlargement-Large hands

Enlarged hands and feet with thickened heel pads. Patients are said to have a “doughy” handshake. Often this is when the diagnosis is first entertained by the astute physician as the sensation is so distinct. Image of large lip, large hands, large feet.
 
 

Patient 1:

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Patient 2:

 

This patient has

Patient 3:

 

This patient has