Soft tissue enlargement
Enlarged hands and feet with thickened heel pads. Patients are said to have a “doughy” handshake. Often this is when the diagnosis is first entertained by the astute physician as the sensation is so distinct.
Patient 1:
This is a young woman who was admitted to the hospital for surgical removal of a pituitary tumor after being diagnosed with acromegaly. She experienced years of symptoms before the diagnosis was made. She had seen multiple doctors but the diagnosis remained elusive. Acromegaly was finally diagnosed when she saw a naturopath.
This patient also has coarse facies and frontal bossing.