Syphilis Rash

The rash of secondary syphilis is typically a nonpruritic papulosquamous rash often involving the palms and soles, associated with mucocutaneous lesions and generalized lymphadenopathy.
 

Patient 1:

This is a previously healthy young woman who developed secondary syphilis with hepatic involvement (note the concurrent jaundice).

Patient 2:

This patient has secondary syphilis.

Patient 3:

This patient has

Patient 4:

This is a middle-aged man with secondary syphilis with characteristic condylomata lata and truncal rash.